What is the ruling on trading in mixed companies and those that are entirely prohibited, while giving charity from the profits to purify them? And is it possible to know the names of the pure companies recommended in Sheikh Al-Manea's fatwa?

We cannot name Saudi companies because we do not have knowledge of them. The questioner can contact scholars specialized in this field. As for the ruling on buying company shares in general, Fatwa No. 66823 should be consulted. It is not permissible to subscribe to companies involved in prohibited activities, even if the intention is to give the profits as charity.