Is it permissible for a son to perform Umrah with his wife, while his parents have not yet performed it, knowing that his mother does not wish to perform it currently?

Filial piety and considering the feelings of one's parents take precedence over others. In the Hadith: "O Messenger of Allah, who among the people is most deserving of my good companionship?" He said, "Your mother." He said, "Then who?" He said, "Your mother." He said, "Then who?" He said, "Your mother." He said, "Then who?" He said, "Your father." Therefore, parents should be taken for Umrah before one's wife, unless it is known that they do not wish for that or would not be bothered by the wife being taken before them.