What is the ruling on praying in clothes that have been defiled by urine after purifying them with water, and reciting the Qur'an in them? And is it permissible to shave the hair between the eyebrows?

Avoiding impurities is a condition for the validity of prayer. Therefore, clothes that have been stained with urine must be purified by washing the affected area with running water. Merely sprinkling or lightly wiping is not sufficient. This is the view of the majority of scholars.

The Maliki school holds that if a person involuntarily passes urine even once a day, the impurity is excused, and they are not obliged to remove it.

As for reciting the Quran while wearing clothes stained with impurities, it is permissible. However, it is preferable to purify them and promptly remove the impurity, as the Prophet (peace be upon him) used to do. Sheikh Ibn Uthaymeen mentioned that it is permissible to recite the Quran while wearing clothes stained with impurities, whether by touching the Mushaf with ablution or reciting from memory.

Removing hair between the eyebrows is permissible.