What is the meaning of Allah Almighty's saying: "And Allah is predominant over His affair"?

The noble verse: "And Allah is predominant over His affair" (Quran 12:21) came in the context of the discourse about Yusuf (peace be upon him). Interpreters have differed regarding the meaning of the pronoun "His" (هاء) in "His affair" (أمره). Some said it refers to Allah Almighty, meaning that nothing overcomes Allah, but rather He is predominant over His affair. Others said it refers to Yusuf, meaning that Allah manages his affairs, encompasses him, and protects him from the plots of schemers.