What is the ruling on a grandmother's will in which she requests not to see her granddaughter in her life or death, and disowns her until the Day of Judgment?

First, if you are innocent of the accusation and did not touch her money, then there is nothing against you. Be patient and seek reward from Allah.

Second, a will that prevents someone from visiting the deceased's neighborhood or attending their burial and mourning is a forbidden will, as it promotes قطعيعة (severing ties). It is not obligatory to execute it. Only wills that involve an act of worship or righteousness should be executed. Jurists stipulate that the bequeathed item must not be an act of disobedience, and this will is closer to sin and severing ties of kinship.