Is a person's prayer unacceptable if he quarrels with his brother who blasphemes God and abuses his parents, and refuses reconciliation, and what should one do with him?

You are rewarded for maintaining ties with your brother who cuts you off, based on the Prophet Muhammad's (peace be upon him) saying: "The one who maintains ties is not the one who reciprocates, but the one who maintains ties is he who, when his kinship is severed, re-establishes it." There is no sin upon you for not maintaining ties with him if he curses Allah and his parents, but you must advise him and remind him of the gravity of cursing Allah and being disobedient to parents. As for him being bewitched, Allah knows best. If signs of sorcery appear on him, guide him to treatment, and do not accuse his wife or her mother of sorcery without proof.