Which of the three mentioned estimations is meant by the estimation of invalidation?

The meaning of the Hadith (definition): "On the hand is what it has taken until it returns it," is that its generality indicates that the item remains the responsibility of the trustee until he returns it, unless it perishes due to a cause beyond his control and without negligence. This is not a guarantee of indemnity for what perishes, but rather an obligation to return what has not perished. However, if it perishes due to negligence, then he is liable.