Is it permissible to hold the Mushaf with both hands during the night vigil prayer (Qiyam al-Layl) when reciting long surahs to overcome fatigue and weak eyesight? And how can a Muslim woman increase her trust and certainty in Allah and get rid of the negative thoughts instilled in her by a former friend, which cast doubt on the answering of prayers and having a good opinion of Allah?

It is permissible to carry the Mus-haf during prayer, though it is better to place it on a stand to avoid the assertion that the prayer is invalid. To improve your perception of Allah, recall His attributes, Glorified be He, and His many blessings. Furthermore, abandoning the companionship of the mentioned girl is absolutely correct. You should seek the company of righteous and pious people, while being certain of a response when supplicating, for one of the greatest causes for the acceptance of supplication is to supplicate with certainty of a response.