How can one overcome psychological pain resulting from pressures and calamities, following the example of the Prophets and the righteous, applying Islam practically, and attaining wisdom?

Enduring life's hardships and pains is achieved through patience, as Allah Almighty said: "So be patient, as were those of determination among the messengers," and "And be patient over what has befallen you. Indeed, that is of the matters [requiring] determination." The practical application of Islam is achieved by obeying commands, avoiding prohibitions, and adhering to its etiquettes. Wisdom is attained through beneficial knowledge, acting upon it, and through supplication. Wisdom has been interpreted as the Quran and its understanding, knowledge and jurisprudence, accuracy in speech, piety, and awe [of Allah]. This is accomplished by seeking knowledge with sincerity, diligence, perseverance, striving against the self to act upon it, and associating with the righteous.