What is the ruling on missing the Maghrib and 'Asr prayers due to sleep induced by tranquilizers resulting from psychological conditions, and is it permissible to pray Maghrib while under the influence of tranquilizers and lacking khushu' (devotional focus)?

It is permissible to take a sedative if you are in need of it, and you must take measures to wake up. If sleep overwhelms you, there is no sin. Some scholars permit combining the Dhuhr and Asr prayers by praying them early if you know that you will not wake up for the Asr prayer. A prayer performed without khushu' (devotion) is valid as long as you fulfill its conditions and pillars.