Is a supplication answered when drinking Zamzam water, even if it is not in Mecca?

The water of Zamzam is for whatever it is drunk for. This includes drinking it in Mecca or outside of it. The Prophet, peace and blessings be upon him, transported Zamzam water to Medina, and Aisha used to transport it, which indicates the permissibility of transporting it and seeking blessings from it wherever one may be. So, whoever drinks it with sincere intention will attain what they intended.