Is there a type of impurity called "datol"? Does it invalidate prayer?

The fundamental principle concerning things is purity. If the composition of a substance includes something impure, such as alcohol, and this impurity was added before the substance transformed into another material, then it is ruled to be impure. Prayer is not permissible, nor is it valid, if any trace of it is found on the body or clothing. However, if it is not known that the compound contains impure substances, then prayer performed with it is valid.