How can the hadiths that indicate that Allah made Makkah sacred on the day He created the heavens and the earth be reconciled with the hadiths that mention that Ibrahim (peace be upon him) was the one who made it sacred, taking into consideration the hadith: "Allah ordained the destinies of creation fifty thousand years before He created the heavens and the earth"?

There is no contradiction between the hadiths that state Allah made Makkah sacred on the day He created the heavens and the earth, and the hadiths that say Ibrahim (peace be upon him) made Makkah sacred. The pre-ordination in the Preserved Tablet of everything that occurs in the universe does not prevent Allah from ordaining something again in a specific way that aligns with the initial decree. Moreover, Allah Almighty decreed the sanctity of the Sacred House, manifested it in existence, and made it a religious law and a faith.