What is the ruling on taking an amount of 60,0, with the commitment to pay 1,500 monthly, regardless of profit or loss, and is it obligatory to return the full amount after a loss?

If the loan is a "Hasan" (good) loan without an increase, then it is legally commendable, and its giver will be rewarded for it. However, if the intention behind it is speculation or investment with a guarantee of the principal and its return with a monthly installment, then this is a void contract and usury (riba). It must be revoked and one must repent from it. Guaranteeing the principal is not permissible under this void condition. The principal is only guaranteed in case of loss due to negligence or transgression.