How can one be patient with loneliness and isolation and overcome the self's anxieties and weaknesses, especially with the feeling of not deserving happiness?

It is advisable to continue being patient and seeking reward from Allah Almighty for the tribulation. As for work, a woman's work is not forbidden if it adheres to the strictures of Sharia (definition), especially when there is a dire need for it. To combat loneliness and isolation, one can look for work near family to care for the elderly father, or live with virtuous sisters, or offer housing to a family that does not include non-mahram (definition) men, or participate in charitable work with women's associations, or join sessions for learning the Quran and beneficial knowledge. It is also recommended to set a varied daily schedule to eliminate free time.