Is it permissible to combine between the madhhabs by following the most sound opinion for the Maliki, based on what Al-Dasuqi transmitted from his shaykhs regarding its permissibility?

The default for a Muslim is to follow the evidence from the Qur'an and Sunnah, and to emulate whoever's ijtihad (independent reasoning) he believes to be sound in matters where there is no direct evidence. He is not obligated to follow a specific madhhab (school of thought) or person. Ibn Taymiyyah said: "No Muslim is obligated to imitate a specific scholar in everything he says, nor is any Muslim obligated to adhere to the madhhab of a particular person. Everyone's statements can be accepted or rejected, except for the Messenger of Allah, peace and blessings be upon him."

There is no excuse for someone who follows an opinion knowing that the evidence is contrary to it. Combining opinions from different madhahib (talfiq) is permissible unless it is in a single issue or with the intention of seeking out concessions without legitimate shar'i (Islamic legal) evidence, because whoever seeks out the concessions of every scholar will accumulate all evils within himself.