Is it permissible for a woman who is harmed by her husband's ill-manners, drug abuse, and abandonment to file a lawsuit for divorce in court, especially if she does not have a guardian?

If the husband is a drug addict and abandons his wife without justification, and the wife has tried to reform him but he did not respond, then there is no blame upon her for seeking divorce from him; in fact, it is preferable. It is permissible for the woman to take her case to the court herself without the need for her guardian, as the guardian is a condition for marriage, not for seeking divorce.